2080 Ventures · Investor guides
32 Series B VC firms in United States
Compare 32 Series B VC firms in United States, including Autotech Ventures, BITKRAFT Ventures, Index Ventures. Explore focus areas, stages and published contacts with 2080 Ventures.
32matching directory firms
18published contacts
18headquarters specified
Most frequent stage tags in this selection: Series A (32), Series B (32), Seed (28). These counts describe this directory, not total market activity.
Compare Series B VC firms in United States
Use this comparison to check fit before contacting a firm. Country tags describe reported locations or country-list membership; they do not establish where a firm is willing to invest.
| Firm | Location | Focus | Stage | Website |
|---|---|---|---|---|
 Autotech Ventures | Menlo Park, California, United States | AI & ML, Automotive, Deep Tech & Hard Science, Enterprise | Early Stage, Late Stage, Pre-Seed, Seed | autotechvc.com |
 BITKRAFT Ventures | Denver, Colorado, United States | AI & ML, AR & VR, Big Data & Analytics, Consumer | Early Stage, Initial Coin Offering, Late Stage, Pre-Seed | bitkraft.vc |
 Index Ventures | San Francisco, California, United States | AI & ML, AR & VR, Biotech, Cybersecurity | Early Stage, Late Stage, Pre-Seed, Seed | indexventures.com |
 Lerer Hippeau | New York, New York, United States | Big Data & Analytics, Crypto & Blockchain, Cybersecurity, E-Commerce | Convertible Note, Debt, Early Stage, Late Stage | lererhippeau.com |
 Meritech Capital Partners | Palo Alto, California, United States | Big Data & Analytics, Cloud, Consumer, Enterprise | Early Stage, Late Stage, Pre-Seed, Private Equity | meritechcapital.com |
 Pantera Capital | Menlo Park, California, United States | Consumer, Crypto & Blockchain, Enterprise, Fintech | Early Stage, Initial Coin Offering, Late Stage, Seed | panteracapital.com |
 Plug and Play | Sunnyvale, California, United States | Agriculture, Climate & Sustainability, DTC, Energy | Early Stage, Non Equity Assistance, Private Equity, Seed | plugandplaytechcenter.com |
 Polaris Partners | Boston, Massachusetts, United States | Advertising, Biotech, Enterprise, Fintech | Early Stage, Late Stage, Pre-Seed, Private Equity | polarispartners.com |
 Redpoint | San Mateo, California, United States | Consumer, Crypto & Blockchain, Fintech, Healthcare | Early Stage, Late Stage, Seed, Series A | redpoint.com |
 S3 Ventures | Austin, Texas, United States | Developer Tools, Enterprise, Fintech, Healthcare | Early Stage, Late Stage, Pre-Seed, Seed | s3vc.com |
 Sapphire Ventures | Austin, Texas, United States | AI & ML, Big Data & Analytics, Crypto & Blockchain, Cybersecurity | Early Stage, Late Stage, Pre-Seed, Seed | sapphireventures.com |
 Scale Venture Partners | Foster City, California, United States | AI & ML, Cloud, Cybersecurity, Devops | Early Stage, Late Stage, Seed, Series A | scalevp.com |
 SOSV | Princeton, New Jersey, United States | AI & ML, Advertising, Agriculture, Big Data & Analytics | Early Stage, Growth, Pre-Seed, Seed | sosv.com |
 Trinity Ventures | Menlo Park, California, United States | Advertising, Big Data & Analytics, Cloud, Consumer | Early Stage, Late Stage, Pre-Seed, Seed | trinityventures.com |
 Union Square Ventures | New York, New York, United States | AI & ML, Advertising, Climate & Sustainability, Consumer | Early Stage, Late Stage, Pre-Seed, Seed | usv.com |
 Versant Ventures | Menlo Park, California, United States | Biotech, Enterprise, Fintech, Healthcare | Early Stage, Late Stage, Post-Ipo, Pre-Seed | versantventures.com |
 White Star Capital | New York, New York, United States | AI & ML, DTC, E-Commerce, Enterprise | Early Stage, Late Stage, Pre-Seed, Seed | whitestarcapital.com |
 Playground Global | Palo Alto, California, United States | AI & ML, Aerospace & Space, Automation, Biotech | Early Stage, Seed, Series A, Series B | playground.vc |
 Altos Ventures | United States | AI & ML, Big Data & Analytics, Consumer, E-Commerce | Late Stage, Pre-Seed, Seed, Series A | altos.vc |
 Amasia | United States | AI & ML, Agriculture, Climate & Sustainability, E-Commerce | Pre-Seed, Seed, Series A, Series B | amasia.vc |
 Bedrock | United States | AI & ML, API, Big Data & Analytics, Enterprise | Series A, Series B, Series C | bedrockcap.com |
 Evolution Equity Partners | United States | AI & ML, Cloud, Cybersecurity, Enterprise | Growth, Seed, Series A, Series B | evolutionequity.com |
 ff Venture Capital | United States | AI & ML, Big Data & Analytics, Cloud, Consumer | Debt, Pre-Seed, Seed, Series A | ffvc.com |
 FJ Labs | United States | AI & ML, Big Data & Analytics, Construction, Consumer | Late Stage, Pre-Seed, Seed, Series A | fjlabs.com |
 Greylock | United States | AI & ML, Consumer, Crypto & Blockchain, Deep Tech & Hard Science | Early Stage, Late Stage, Pre-Seed, Seed | greylock.com |
 Hatzimemos / Libby | United States | Climate & Sustainability, DTC, Education, Energy | Series A, Series B | h-l.vc |
 Jump Capital | United States | Enterprise, Fintech, Internet & Mobile, Media | Seed, Series A, Series B | jumpcap.com |
 Portfolia | United States | AI & ML, Agriculture, Climate & Sustainability, Cloud | Pre-Seed, Seed, Series A, Series B | portfolia.co |
 Spero Ventures | United States | AI & ML, Big Data & Analytics, Education, Health & Wellness | Seed, Series A, Series B | spero.vc |
 Two Sigma Ventures | United States | Biotech, Consumer, Crypto & Blockchain, Enterprise | Seed, Series A, Series B | twosigmaventures.com |
 U.S. Venture Partners | United States | Cloud, Consumer, Cybersecurity, Healthcare | Series A, Series B | usvp.com |
 VMG Partners | United States | Big Data & Analytics, Consumer, Creator Economy, Cybersecurity | Late Stage, Pre-Seed, Seed, Series A | vmgpartners.com |
Build an outreach list that fits your company
Connect growth capital to a repeatable operating model. Prepare cohort performance, margins, leadership hiring priorities, and scenarios for deploying a larger round.
For United States, confirm location eligibility before preparing a full pitch: where must the company be incorporated, where should the team operate, and does the investor back companies expanding into the market? A local office alone does not answer those questions.
- Check the mandate. Confirm sector, stage, geography, check size, and whether the firm leads or follows rounds.
- Find the relevant partner. Read current team profiles and recent investments before asking for an introduction.
- Make the fit specific. Explain your product, customer evidence, round size, and why this firm is a match.
- Use the correct submission route. A general office contact may not accept investment pitches. Look for a current pitch form or a partner’s published instructions.
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How these guides are compiled. Directory labels may include source-list classifications. Confirm current activity and investment preferences directly with the firm.